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</a> For the vast majority of primary malignant tumors, there are no known risk factors or family history. ÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂThe thinking is that all malignant brain tumors are genetic in origin, even if thereÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂs not a family history or a mutated gene thatÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂs been passed on,ÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂàsays Yong. ÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂIn these cases, a random mutation occurring in any one of the brainÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂs hundreds of billions of cells could lead to brain cancer.ÃÂÃÂÃÂâÃÂÃÂÃÂÃÂÃÂÃÂÃÂÃÂ